From Chemical Topology to Molecular Machines (Nobel Lecture)
نویسندگان
چکیده
منابع مشابه
Multiscale modeling of biological functions: from enzymes to molecular machines (Nobel Lecture).
A detailed understanding of the action of biological molecules is a pre-requisite for rational advances in health sciences and related fields. Here, the challenge is to move from available structural information to a clear understanding of the underlying function of the system. In light of the complexity of macromolecular complexes, it is essential to use computer simulations to describe how th...
متن کاملFrom Chemical Topology to Molecular
T o a large extent, the eld of “molecular machines” started aer several groups were able to prepare reasonably easily interlocking ring compounds (named catenanes for compounds consisting of interlocking rings and rotaxanes for rings threaded by molecular laments or axes). Important families of molecular machines not belonging to the interlocking world were also designed, prepared and studied ...
متن کاملNobel Lecture
Ladies and Gentlemen! It gives me great pleasure to be giving the Nobel Lecture before you. In it I shall be reporting on the results of my research for which the Royal Caroline Institute permit me here once again to give public expression of my deepest gratitude has awarded me the Nobel Prize. Naturally I can only present a fraction of these results and I shall have to content myself with tell...
متن کاملNobel Lecture
The sense organs respond to certain changes in their environment by sending messages or signals to the central nervous system. The signals travel rapidly over the long threads of protoplasm which form the sensory nerve fibres, and fresh signals are sent out by the motor fibres to arouse contraction in the appropriate muscles. What kind of signals are these, and how are they elaborated in the sa...
متن کاملNobel Lecture
Up until the year 1921 it was not known how the stimulation of a nerve influenced the effector organ's function, in other words, in what way the stimulation was transmitted to the effector organ from the nerve-ending. In general it was thought that it came about through direct transmission of the stimulation wave from the nerve fibre to the effector organ. But the possibility of transmission by...
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ژورنال
عنوان ژورنال: Angewandte Chemie International Edition
سال: 2017
ISSN: 1433-7851
DOI: 10.1002/anie.201702992